Biology

Cell Cycle and Cancer Biology

By: Alicia Snowden and Tony Neal

p53 and Cell Cycle

In order for a living being to survive; their cells must go through a necessary process of replication and division.  This process is called the cell cycle.  The cell cycle is a multi-step cycle that includes the following phases: G1 phase, S phase, G2 phase, Mitosis, and cytokinesis.  Since the cell cycle is necessary for…

p53 as Transcription Factor

The central dogma states that DNA is transcribed into RNA, which is then translated into proteins.  The central dogma must be under strict regulation, which is accomplished by transcription factors.  Transcription factors are molecules/proteins that control whether or not a gene is expressed (DNA made into protein).  As a transcription factor, p53 regulates the production/expression…


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